HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 6-bromo-N-(10-imidazol-1-yldecyl)benzo[cd]indol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Reactant | 10-(1H-imidazol-l-yl)decanamine, dihydrochloride | HCID 131715466 | — |
| Reactant | HCID 178527759 | HCID 178527759 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-bromo-N-(10-imidazol-1-yldecyl)benzo[cd]indol-2-amine | HCID 178419290 | 70% |
Reaction Steps
A mixture of 2.8 g of 10-(1H-imidazol-1-yl)decanamine, dihydrochloride was treated with 2 ml of 10N sodium hydroxide in an ethanol-water mixture giving the base derivative. To this base was added 25 ml of ethanol, 2.33 g of 6-bromo-benz[cd]indole-2-thiol and 3 g of mercuric acetate. The procedure of Example 1 was then followed, giving 2.8 g of the desired product, mp 115°-116° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728663 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-db56989a141a4068a05c7481a76e521f |
| Source note | uspto-grants-1988_03 |