1H-Imidazole-1-pentanamine → HCID 178419291, compound

HRID 568500Notes

Reaction equation

HRID 568500 reaction equation
[Br:1][C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6](S)[C:5]=3[CH:12]=[CH:13][CH:14]=2.[N:15]1([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][NH2:25])[CH:19]=[CH:18][N:17]=[CH:16]1>C(O)C>[Br:1][C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6]([NH:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1)[C:5]=3[CH:12]=[CH:13][CH:14]=2

Participants

4

Reactant 2

HCID 71384341H-Imidazole-1-pentanamineHCID 178527759HCID 178527759, compound

Product 1

HCID 178419291HCID 178419291, compoundYield 19.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 5.3 g of 6-bromo-benz[cd]indole-2-thiol, 3.1 g of 5-(1H-imidazol-1-yl)pentanamine, 100 ml of ethanol and 6.3 g of mercuric acetate was reacted as described in Example 1, giving 1.5 g of the desired product, mp 138°-140° C.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-0cf46d6775184ecb91feb2f9cdcf278c
Source dataset
uspto-grants-1988_03
Patent number
US04728663

Reaction notes

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