HCID 14189449, compound → HCID 178419794, compound

HRID 568502Notes

Reaction equation

HRID 568502 reaction equation
[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH2:18])[CH:5]=[CH:4][N:3]=[CH:2]1.[N:19]1[C:27]2[C:22]3[C:23](=[CH:28][CH:29]=[CH:30][C:21]=3[C:20]=1S)[CH:24]=[CH:25][CH:26]=2>C(O)C>[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:20]2[C:21]3[CH:30]=[CH:29][CH:28]=[C:23]4[C:22]=3[C:27](=[CH:26][CH:25]=[CH:24]4)[N:19]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

4

Reactant 2

HCID 14189449HCID 14189449, compoundHCID 178527764HCID 178527764, compound

Product 1

HCID 178419794HCID 178419794, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.5 g of 12-(1H-imidazol-1-yl)dodecanamine, 1.9 g of benz[cd]indole-2-thiol, 3.4 g of mercuric acetate and 400 ml of ethanol was reacted as described in Example 1. The crude product was purified by dissolving it in chloroform and chromatographing it on a silica gel column, eluting with 10% methanol in chloroform giving 490 mg of the desired product, mp 95°-97° C.

Workup

  1. customwas reacted
  2. customThe crude product was purified
  3. dissolutionby dissolving it in chloroform
  4. washchromatographing it on a silica gel column, eluting with 10% methanol in chloroform giving 490 mg of the desired product, mp 95°-97° C.

Sources & evidence

ORD record
ord-e16c9ad391ce4c6ebfa5578bd2068773
Source dataset
uspto-grants-1988_03
Patent number
US04728663

Reaction notes

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