1H-Imidazole-1-propanamine → HCID 178477837, compound

HRID 568504Notes

Reaction equation

HRID 568504 reaction equation
[Cl:1][C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6](S)[C:5]=3[CH:12]=[CH:13][CH:14]=2.[N:15]1([CH2:20][CH2:21][CH2:22][NH2:23])[CH:19]=[CH:18][N:17]=[CH:16]1>C(O)C>[Cl:1][C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6]([NH:23][CH2:22][CH2:21][CH2:20][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1)[C:5]=3[CH:12]=[CH:13][CH:14]=2

Participants

4

Reactant 2

HCID 787361H-Imidazole-1-propanamineHCID 178527785HCID 178527785, compound

Product 1

HCID 178477837HCID 178477837, compoundYield 74.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 1 g of 6-chloro-benz[cd]indole-2-thiol, 540 mg of 3-(1H-imidazol-1-yl)propanamine, 1.26 g of mercuric acetate and 100 ml of ethanol was reacted as described in Example 1, giving 1 g of the desired compound, mp 177°-178° C.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-b25c902a267740579607b45f2ae31abe
Source dataset
uspto-grants-1988_03
Patent number
US04728663

Reaction notes

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