Boron tribromide → HCID 135856719, compound

Participants

Reaction Steps

A solution of 6.94 g of 3-(4-methoxyphenyl)thieno[2,3-d]isoxazole in 40 ml of dichloromethane was treated dropwise with 1M solution of boron tribromide in dichloromethane. A precipitate appeared after a few minutes. The suspension was stirred overnight and thereafter quenched with 10% hydrochloric acid. Extraction with ether followed by washing and drying gave a solid which was found to be contaminated with 5% of the starting material. The crude product was fed to an alumina column packed in ether.

Provenance & Evidence