HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine → Fadrozole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine | HCID 15294718 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Fadrozole | HCID 59693 | — |
Reaction Steps
A solution of 1.6 g of 5-(p-cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine in 50 ml of ethyl acetate is hydrogenated at atmospheric pressure with 0.2 g of 5% palladium on charcoal until the theoretical uptake of hydrogen is complete. The catalyst is filtered, and the solvent evaporated to yield the title compound, m.p. 117°-118°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728645 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-e6aafd87899644d189a80def73fbbd5b |
| Source note | uspto-grants-1988_03 |