m-Chloroperbenzoic acid → HCID 20150758, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 10.11-dihydro-7-hydroxydibenzo [b,f][1,4]thiazepin (2.2 g,10 mmoles) and m-chloroperbenzoic acid (3.4 g,20 mmoles) in methylene chloride (250 ml) was stirred at 0° C. for 1 hour. The reaction mixture was treated with 4 g of calcium hydroxide for 15 minutes and was then filtered. The filtrate was chromatographed on silica gel, eluting with 5% methanol in chloroform, to yield the title compound, m.p. 202° (dec.).

Provenance & Evidence