Acetic Acid → HCID 14126436, compound

Participants

Reaction Steps

To 5-methoxy-2,2-dimethylbenzothiazolidine (14.6 gm; 75 mmoles) in 50 ml dimethoxyethane and 5 ml isopropanol was added sodium borohydride (4.0 gm; 0.1 mole). The reaction mixture was stirred at room temperature for 1 hour. The mixture was then poured over 5 N acetic acid, extracted with methylene chloride, washed with brine, dried (Na2SO4) and concentrated in vacuo. The residue was recrystallized from hexane to yield the title compound, m.p. 68°-69° C. in nearly quantitative yield.

Provenance & Evidence