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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568603Generated: November 1, 2026

1-Chloro-2-nitrobenzene → N-(4-methoxybenzyl)-2-nitroaniline

https://huagongshe.com/reaction/568603

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-2-nitrobenzeneHCID 6945—
Reactant4-MethoxybenzylamineHCID 75452—
ReactantAmmonium AcetateHCID 517165—
ProductN-(4-methoxybenzyl)-2-nitroanilineHCID 2920606100%

Reaction Steps

Reaction of 2-chloronitrobenzene (10 g, 63 mmole), 4-methoxybenzylamine (52.1 g, 380 mmole) and ammonium acetate (4.6 g) substantially as described in 1C above producted 15 g (100%) of title compound as orange crystals: mp 75°-78°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04728741
Source datasetuspto-grants-1988_03
ORD IDord-b81ed304d81b42008b8f0c85a0e95b8f
Source noteuspto-grants-1988_03