HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 14012552, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 2,3-Dichloroanisole | HCID 16126 | — |
| Reactant | 3-Furoyl chloride | HCID 2776123 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Carbon Disulfide | HCID 6348 | — |
| Product | HCID 14012552 | HCID 14012552 | — |
Reaction Steps
3-Furoyl chloride (18.0 g) and 2,3-dichloro anisole (24.7 g) are dissolved in 125 ml of CS2 and treated with AlCl3 (18.7 g), first at 5° C. and then at room temperature. After five hours the reaction is quenched with ice/HCl an extracted with CH2Cl2. Drying and evaporation gives a crystalline product that is titurated with hexane to yield 4-(3-furoyl)-2,3-dichloroanisole, mp 118°-122° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728662 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-b465b0a01d154c1caf8e6a21adf99cca |
| Source note | uspto-grants-1988_03 |