HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → HCID 135991845, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | HCID 14012491 | HCID 14012491 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | HCID 135991845 | HCID 135991845 | — |
Reaction Steps
A solution of 5-chloro-3-(2-fluorophenyl)-6-methoxy-1,2-benzisoxazole (1 g) and boron tribromide (1.3 ml) in dichloroethane (30 ml) is refluxed for about 24 hours. The reaction mixture is poured onto ice-water and extracted with dichloromethane to give a solid of 5-chloro-3-(2-fluorophenyl)-6-hydroxy-1,2-benzisoxazole, mp 180°-182° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728662 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-e97cbecfdbf14b5bbcaae4747a307f0d |
| Source note | uspto-grants-1988_03 |