反应详情

温度

60 °C

A mixture of 19 g of E-3-chloro-2',5'-difluoro-2-hydroxy-4-methoxybenzophenone oxime and 10 ml of acetic anhydride was warmed at 60° C. for 30 minutes. On cooling the mixture solidifies. The residue is partitioned between ethylacetate and 10% NaHCO3. The ethylacetate extract is washed with water, dried over Na2SO4 and evaporated to give E-3-chloro-2',5'-difluoro-2-hydroxy-4-methoxybenzophenone O-acetyl oxime, mp 130°-131° C.

1. temperatureOn cooling the mixture
2. customThe residue is partitioned between ethylacetate and 10% NaHCO3
3. extractionThe ethylacetate extract
4. washis washed with water
5. dry with materialdried over Na2SO4
6. customevaporated