HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Chloro-2,4-dimethoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methane, dichloromethoxy- | HCID 21004 | — |
| Reactant | 2-Chloro-1,3-dimethoxybenzene | HCID 13015717 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Chloro-2,4-dimethoxybenzaldehyde | HCID 13343705 | — |
Reaction Steps
2-chlororesorcinol dimethyl ether (3.4 g) is dissolved in 20 ml of CH2Cl2 and TiCl4 (4.3 ml) is added. To this solution is added dichloromethyl methyl ether (2.3 g). After 30 minutes the reaction mixture is poured into H2O and extracted with ether. Drying and evaporation gives 3-chloro-2,4-dimethoxybenzaldehyde, mp 107°-108° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728662 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-bb754afce9a54c8ebd5bde9bc76de249 |
| Source note | uspto-grants-1988_03 |