HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Chloro-4-methoxysalicylaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 3-Chloro-2,4-dimethoxybenzaldehyde | HCID 13343705 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | 3-Chloro-4-methoxysalicylaldehyde | HCID 13343706 | — |
Reaction Steps
3-chloro-2,4-dimethoxybenzaldehyde (2.75 g) is refluxed for 30 minutes in 20 ml of dichloroethane containing 1.8 g of AlCl3. The reaction mixture is then poured into H2O and extracted with CH2Cl2. Evaporation and recrystallization from isopropanol gives 3-chloro-2-hydroxy-4-methoxybenzaldehyde, mp 125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728662 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-47366e9ecb2d4c20b9909f514d30537b |
| Source note | uspto-grants-1988_03 |