反应详情

Hydroquinone monobenzyl ether (100.0 g, 0.50 mol) was dissolved in pyridine (600 ml), followed by dropwise adding to the solution, a solution of p-(1-methyl-heptyloxy)benzoic acid chloride (122.2 g, 0.45 mol) dissolved in toluene (600 ml), under ice cooling, agitating the mixture for 2 hours while keeping the temperature at about 50°-60° C., allowing it to stand overnight, thereafter adding toluene (3,000 ml) and water (2,000 ml), agitating the mixture, washing the toluene layer with 6N-HCl, then with 2N-NaOH aqueous solution and further with water until the wash water became neutral, distilling off toluene and recrystallizing the residue from ethanol to obtain p-(1-methyl-heptyloxy)-benzoic acid p-benzyloxyphenyl ester (121.0 g).

1. additionby dropwise adding to the solution
2. customat about 50°-60° C.
3. waitto stand overnight
4. washwashing the toluene layer with 6N-HCl
5. distillationdistilling off toluene
6. customrecrystallizing the residue from ethanol