Butyric Acid → HCID 178439844, compound

HRID 568806Notes

Reaction equation

HRID 568806 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[NH:11][C:12]([CH2:14][CH2:15][CH3:16])=O)[NH:7][C:6](=[O:17])[C:5]2([CH3:19])[CH3:18].C(O)(=O)CCC>>[CH2:14]([C:12]1[NH:11][C:10]2[CH:9]=[C:8]3[NH:7][C:6](=[O:17])[C:5]([CH3:19])([CH3:18])[C:4]3=[CH:3][C:2]=2[N:1]=1)[CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 264Butyric AcidHCID 20149408HCID 20149408, compound

Product 1

HCID 178439844HCID 178439844, compound

Procedure

According to the process of Example 5, from 0.7 g. (2.7 mmole) 5-amino-6-n-propylcarbonylamino-3,3-dimethylindolin-2-one and 7 ml. butyric acid, after 1 hour at 100° C., there is obtained 0.4 g. (61% of theory) of the title compound; m.p. 284°-285° C.

Workup

  1. customthere is obtained 0.4 g

Sources & evidence

ORD record
ord-a5e464f77b8541098957b8a10711dbc5
Source dataset
uspto-grants-1988_03
Patent number
US04730003

Reaction notes

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