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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56881Generated: October 30, 2026

Trifluoroacetic acid → HCID 117622982, compound

https://huagongshe.com/reaction/56881

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 117622874HCID 117622874—
ProductHCID 117622982HCID 117622982—

Reaction Steps

119 mg (purity 91%, 0.21 mmol) of tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-[1-(trifluoromethyl)cyclobutyl]propanoate (racemate) were hydrolysed with TFA according to General Method 6A. Yield: 91 mg (purity 69%, 65% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434690B2
Source datasetuspto-grants-2016_09
ORD IDord-f8747330a1b9407fb93bdd734958ac60
Source noteuspto-grants-2016_09