HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13315132, compound → 6453-27-6
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13315132 | HCID 13315132 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 6453-27-6 | HCID 317218 | 68.6% |
Reaction Steps
660 mg of 6-nitro-3-methylthio-β-carboline are hydrogenated in 50 ml of N-methylpyrrolidone with 3 g of Raney nickel at 50 bar of H2 pressure and 60° C. for 2 hours. After filtering, it is evaporated and the residue chromatographed on silica gel with methylene chloride/ethanol=10:2 as eluant. 320 mg of 6-amino-β-carboline as oil are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04731358 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-5beb6bfc5d0d4fdf8829aadb4f58c767 |
| Source note | uspto-grants-1988_03 |