Ethyl 3-hydroxy-2-nitrobutanoate → HCID 54371401, compound

HRID 569088Notes

Reaction equation

HRID 569088 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[NH:10][C:11]3[C:16]([C:17]=2[C:18]=1[CH3:19])=[C:15]([CH2:20][OH:21])[CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2].C(OC(=O)C([N+]([O-])=O)C(O)C)C>>[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[NH:10][C:11]3[C:16]([C:17]=2[C:18]=1[CH3:19])=[C:15]([CH:20]=[O:21])[CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 20470476Ethyl 3-hydroxy-2-nitrobutanoateHCID 53753831HCID 53753831, compound

Product 1

HCID 54371401HCID 54371401, compound

Procedure

The synthesis takes place according to the method described in example 1 from 5-hydroxymethyl-4-methyl-beta-carboline-3-carboxylic acid ethyl ester, which in turn is prepared according to example 2 from 2-nitro-3-hydroxybutyric acid ethyl ester in 5 stages.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-9c03ed87402d4ec1ad46dd73b81a0516
Source dataset
uspto-grants-1988_03
Patent number
US04731365

Reaction notes

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