Pyridine → HCID 67882225, compound

Participants

Reaction Steps

A solution of 0.2 g of (R)-1-O-(4-chloro-butyryl)-2-O-(methylcarbamoyl)-3-O-octadecylglycerine in 10 ml of pyridine is heated to 80° C. for 16 hours. The solution is evaporated and the residue is treated with toluene by azeotropic distillation. The residue is recrystallized from ether. There is obtained 1-[3-[[(R)-2-[(methylcarbamoyl)oxy]-3-(octadecyloxy)propoxy]carbonyl]-propyl]pyridinium chloride of melting point 53°-60° C. (dec.).

Provenance & Evidence