HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → HCID 13455834, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | 8-Acetyl-1,6,8-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione | HCID 13453492 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 13455834 | HCID 13455834 | — |
Reaction Steps
A solution of (±)-2-acetyl-2,7,12-trihydroxy-1,2,3,4-tetrahydronaphthacene-6,11-dione (740 mg; 2.1 mmol) and ethylene glycol (280 mg; 4.4 mmol) in 400 ml of benzene, in the presence of a catalytic quantity of paratoluenesulfonic acid, is heated under reflux for 12 hours in a 500 ml round-bottomed flask. The flask is equipped with a "Dean Stark" apparatus (making it possible to remove the water formed as an azeotrope with benzene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04731468 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-fe54639ac8f24e658ad5297901b822f7 |
| Source note | uspto-grants-1988_03 |