化工社化工社 化学情報印刷レポート · 研究参考用
Succinic anhydride → 2-(3-Methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Succinic anhydride | HCID 7922 | — |
| 反応物 | N-(3-Methoxybenzylidene)aniline | HCID 555084 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | 2-(3-Methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylic acid | HCID 13361985 | — |
反応手順
A solution of 42.3 gm. of 3-methoxybenzylidenaniline, 20 gm. of succinic anhydride and 200 ml. of xylene was refluxed for 16 hours. The crude product was obtained as a solid via the same workup used for example 1B. Recrystallization from ethyl acetate followed by a second recrystallization from acetonitrile provided 21.0 gm. of colorless crystals, m.p. 145°-149°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04731457 |
| 出典データセット | uspto-grants-1988_03 |
| ORD ID | ord-8ac826c538a24c5ca9b68e7c1c721d98 |
| 出典メモ | uspto-grants-1988_03 |