Diethyl Malonate → HCID 20147153, compound

Participants

Reaction Steps

Reaction of 5-(1-octynyl)-2-thiophenecarboxaldehyde (2.64 g 12 mmole) with diethyl malonate as described in Example 3 yielded the title compound as a yellow oil 4.2 g (96.7%). νmax (film) 2225, 1730, 1615, 865, 805; δ(CDCl3), 0.90(3H, t, J=6 Hz), 1.5(14H, m), 2.32(2H, t, J=6 Hz), 4.30(2H, q, J=7.5), 4.4(2H, q, J=7.5), 7.03 (1H, d, J=3 Hz), 7.23(1H, d, J=3 Hz), 7.76(1H, s).

Provenance & Evidence