Malonic Acid → HCID 20147174, compound

Participants

Reaction Steps

Reaction of 4-(1-octynyl)-2-thiophenecarboxaldehyde (1.1 g, 5 mmole) with malonic acid by the method described in Example 2 yielded the title compound 1.19 g, (91%) as a fawn solid, mp 81° (hexane) νmax (mull) 2600(vb) 1695, 1680, 1625, 965, 940, 830, 760; δ(CDCl3) 0.90(3H, t, J=6 Hz), 1.4(8H, m), 2.37(t, 2H, J=6 Hz), 6.22(H, d, 15 Hz), 7.25(1H, s), 7.40(1H, s), 7.80(d, 1H, J=15 Hz), 11.5(1H, bs).

Provenance & Evidence