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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56953Generated: October 29, 2026

4-[2-(Trifluoromethyl)-1H-imidazol-5-yl]aniline → HCID 117622723, compound

https://huagongshe.com/reaction/56953

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(Trifluoromethyl)-1H-imidazol-5-yl]anilineHCID 117622848—
Reactant2-[4-(5-Chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acidHCID 117622850—
ProductHCID 117622723HCID 117622723—

Reaction Steps

67 mg (0.22 mmol) of 2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) (Example 2.2B) and 49 mg (0.22 mmol) of 4-[2-(trifluoromethyl)-1H-imidazol-5-yl]aniline (Example 1.3B) were reacted according to General Method 1. Yield: 26 mg (22% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434690B2
Source datasetuspto-grants-2016_09
ORD IDord-a705a73311c546fc87b476cb6b0be1e1
Source noteuspto-grants-2016_09