HRID569530

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12919092

未命名化合物

$结构：CC1(C)[C@H](C(=O)O)[C@@H]1/C=C\C(=O)OCCF$

HCID86740321

未命名化合物

PRODUCTS

生成物

$结构：C#CC(OC(=O)[C@@H]1[C@H](/C=C\C(=O)OCCF)C1(C)C)c1cccc(Oc2ccccc2)c1$

HCID86740322

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

Using the procedure of Step F of Example 9, (1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylic acid and α-ethynyl-3-phenoxy-benzyl alcohol were reacted to obtain α-ethynyl-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+47°±1.5° (c=1% in CHCl3).

WORKUP

后处理

customwere reacted