Bromotrimethylsilane → HCID 20147876, compound

HRID 569608Notes

Reaction equation

HRID 569608 reaction equation
C[Si](C)(C)Br.[Cl:6][C:7]1[CH:30]=[C:29]([Cl:31])[CH:28]=[CH:27][C:8]=1[O:9][CH:10]([P:19](=[O:26])([O:23]CC)[O:20]CC)[P:11](=[O:18])([O:15]CC)[O:12]CC>C(Cl)Cl>[Cl:6][C:7]1[CH:30]=[C:29]([Cl:31])[CH:28]=[CH:27][C:8]=1[O:9][CH:10]([P:11](=[O:12])([OH:15])[OH:18])[P:19](=[O:20])([OH:26])[OH:23]

Participants

4

Reactant 2

HCID 76113BromotrimethylsilaneHCID 53813578HCID 53813578, compound

Product 1

HCID 20147876HCID 20147876, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Trimethyl bromosilane (17.3 ml) was added to a stirred solution of tetraethyl (2,4-dichlorophenoxymethylene)-bisphosphonate (5.0 g) in methylene chloride (18 ml). After 3 hours at room temperature, the mixture was evaporated in vacuo, and residual trimethyl bromosilane was removed by repeated evaporation with methylene chloride. The residue was stirred overnight in ethanol and evaporated in vacuo. Crystallization from ether gave the title compound as colourless crystals.

Workup

  1. customthe mixture was evaporated in vacuo, and residual trimethyl bromosilane
  2. customwas removed
  3. customevaporation with methylene chloride
  4. customevaporated in vacuo
  5. customCrystallization from ether

Sources & evidence

ORD record
ord-c59ea58a217945b8be35194056e855e0
Source dataset
uspto-grants-1988_03
Patent number
US04732998

Reaction notes

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