HCID 53949882, compound → HCID 20147863, compound

HRID 569614Notes

Reaction equation

HRID 569614 reaction equation
[CH3:1][O:2][C:3]1[CH:26]=[CH:25][C:6]([O:7][CH:8]([P:17](=[O:24])([O:21]CC)[O:18]CC)[P:9](=[O:16])([O:13]CC)[O:10]CC)=[CH:5][CH:4]=1>C[Si](C)(C)Br>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([O:7][CH:8]([P:17](=[O:18])([OH:24])[OH:21])[P:9](=[O:10])([OH:13])[OH:16])=[CH:25][CH:26]=1

Participants

3

Reactant 1

HCID 53949882HCID 53949882, compound

Product 1

HCID 20147863HCID 20147863, compound

Reagents, catalysts & solvents 1

HCID 76113BromotrimethylsilaneSolvent

Procedure

Tetraethyl (4-methoxyphenoxymethylene)-bisphosphonate (4 g) was dissolved in trimethyl bromosilane (16.4 ml). After 3 hours at room temperature, the mixture was evaporated in vacuo. The remaining oil was heated with absolute ethanol (30 ml) on the steam bath for 2 hours. Evaporaton in vacuo and crystallization from ether gave the title compound as colourless crystals.

Workup

  1. customthe mixture was evaporated in vacuo
  2. temperatureThe remaining oil was heated with absolute ethanol (30 ml) on the steam bath for 2 hours
  3. customEvaporaton in vacuo and crystallization from ether

Sources & evidence

ORD record
ord-35d0685dee33475cb08a962613e6297f
Source dataset
uspto-grants-1988_03
Patent number
US04732998

Reaction notes

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