Fumaric Acid → L-Malic Acid

HRID 569724Notes

Reaction equation

HRID 569724 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[NH4+].[OH-:10].[OH-].[Na+]>>[C:1]([OH:8])(=[O:7])[C@H:2]([CH2:3][C:4]([OH:6])=[O:5])[OH:10]

Participants

3

Reactant 2

HCID 444972Fumaric AcidHCID 22102170HCID 22102170, compound

Product 1

HCID 222656L-Malic Acid

Procedure

Cell mass grown according to example A is suspended in 8 liters of a 240 g/l solution containing fumaric acid (neutralized with NH4OH NaOH in the molar ratio of 2 to 1). After 12 hours of incubation, 237 g of L-malic acid per liter of fermentation liquid is produced.

Sources & evidence

ORD record
ord-138f40d0c46941cea8af9963c9aa0771
Source dataset
uspto-grants-1988_03
Patent number
US04734368

Reaction notes

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