Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 569740Generated: October 25, 2026

Tetrahydrofuran → Indole-5-carboxaldehyde

https://huagongshe.com/reaction/569740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant(1H-indol-5-yl)methanolHCID 2773458—
CatalystHCID 178418406HCID 178418406—
SolventDichloromethaneHCID 6344—
ProductIndole-5-carboxaldehydeHCID 589040—

Reaction Steps

51.1 g (0.347 mole) of 6c are stirred analogously to Example 1b in 1,900 ml of CH2Cl2 and 200 ml of tetrahydrofuran with 190 g (2.18 moles) of manganese(IV) oxide at 20° C. overnight.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04734407
Source datasetuspto-grants-1988_03
ORD IDord-6951838fb0ee451590cf8f924ceb8212
Source noteuspto-grants-1988_03