HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminum hydride → 2,1-Benzisothiazole-6-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminum hydride | HCID 14487 | — |
| Reactant | Methyl benzo[c]isothiazole-6-carboxylate | HCID 20146254 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,1-Benzisothiazole-6-methanol | HCID 20146242 | — |
Reaction Steps
5.8 g (0.03 mole) of 10a are stirred analogously to Example 1a in 80 ml of tetrahydrofuran with 58.8 ml (0.09 mole) of DIBAL (1.53 molar solution in toluene) at -60° C. to -70° C. overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04734407 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-2958ce6caf53430b883046e3edab913c |
| Source note | uspto-grants-1988_03 |