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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 569748Generated: October 29, 2026

Lithium Hydroxide → alpha-Amino-alpha-(2,1-benzisothiazol-6-yl)acetic acid

https://huagongshe.com/reaction/569748

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant5-(2,1-Benzisothiazol-6-yl)-2,4-imidazolidinedioneHCID 20146261—
SolventWaterHCID 962—
Productalpha-Amino-alpha-(2,1-benzisothiazol-6-yl)acetic acidHCID 20146233—

Reaction Steps

16.5 g (0.071 mole) of 10d are heated under reflux analogously to Example 3e with 17.0 g (0.71 mole) of lithium hydroxide in 250 ml of water for 20 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04734407
Source datasetuspto-grants-1988_03
ORD IDord-4c4c97a222c744318ba7490b91efe412
Source noteuspto-grants-1988_03