HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 3(2H)-Pyridazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 357537 | HCID 357537 | — |
| Reactant | HCID 13233881 | HCID 13233881 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3(2H)-Pyridazinone | HCID 68153 | — |
| Product | HCID 12200169 | HCID 12200169 | — |
Reaction Steps
Using the procedure of this Example, reaction of 4,5-dihydro-2-methyl-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone and 4,5-dihydro-2-(2-hydroxyethyl)-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone with bromine in acetic acid gives 6-[4-1H-imidazol-1-yl)phenyl]-2-methyl-3(2H)-pyridazinone (13e) and 2-(2-hydroxyethyl)-6-[4-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone respectively (13f).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04734415 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-a88493fbea9346318aed7c1ae6c3ea66 |
| Source note | uspto-grants-1988_03 |