1,2-Dibromoethane → HCID 14099436, compound

Participants

Reaction Steps

A solution of 3.5 g of 4-(1,6-dihydro-6-oxo-3-pyridazinyl)benzenecarbothioamide, 3.1 g of 1,2-dibromoethane in 75 ml of DMF containing 4.2 g of K2CO3 is heated on a steambath for three hours. The inorganic salts are filtered and the filtrate is evaporated under reduced pressure. The residue is crystallized from ethanol/tetrahydrofuran to yield 1.2 g of the product, 6-[4-(4,5-dihydro-2-thiazolyl)phenyl]-4,5-dihydro3(2H)-pyridazinone mp 236°-238° C.

Provenance & Evidence