Methyl 6-[1-(3-pyridyl)ethenyl]-2-naphthoate → Methyl 6-[1-(3-pyridyl)ethyl]-2-naphthoate

Participants

Reaction Steps

130 mg of Pd/C (10%) are added to 0.25 g (0.86 mmol) of methyl 6-[1-(3-pyridyl)ethenyl]-2-naphthoate in 25 ml of absolute methanol, and hydrogenation is carried out under atmospheric pressure (hydrogen uptake: 40 ml). The catalyst is then removed by filtration, and the solution is evaporated and chromatographed on silica gel using ethyl acetate. 50 mg (20%) of methyl 6-[1-(3-pyridyl)ethyl]-2-naphthoate are obtained as an oil. RF (ethyl acetate): 0.34.

Provenance & Evidence