HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-2-(trifluoromethyl)benzimidazole → HCID 117622619, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-2-(trifluoromethyl)benzimidazole | HCID 19345 | — |
| Reactant | 2-[5-Chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid | HCID 117622549 | — |
| Product | HCID 117622619 | HCID 117622619 | — |
Reaction Steps
68 mg (purity 94%, 0.20 mmol) of 2-[5-chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) (Example 12.1D) and 44 mg (0.22 mmol) of 2-(trifluoromethyl)-1H-benzimidazole-6-amine were reacted according to General Method 1. Yield: 63 mg (60% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-6aac64e77c8e422fbbcd7cb55ae1e4d2 |
| Source note | uspto-grants-2016_09 |