HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine → N-(phenoxyacetyl)glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine | HCID 750 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Phenoxyacetyl chloride | HCID 69703 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-(phenoxyacetyl)glycine | HCID 300109 | — |
Reaction Steps
Glycine (20 mmol) was reacted with distilled phenoxyacetyl chloride (22 mmol) in the presence of NaOH (40 mmol) in a mixture of water and ether as described in Example 5 Part A. The crude product was recrystallized from EtOAc (15 ml) to give title acid (2.38 gm, 57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04734426 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-309526eb23034ca5935b2b96a4878a39 |
| Source note | uspto-grants-1988_03 |