HCID 4321391, compound → N-acetyl-3-acetylthiovalyl-L-proline t-butyl ester

HRID 569874Notes

Reaction equation

HRID 569874 reaction equation
[C:1]([NH:4][C@H:5]([C:13]([OH:15])=O)[C:6]([S:9][C:10](=[O:12])[CH3:11])([CH3:8])[CH3:7])(=[O:3])[CH3:2].[C:16]([NH:19][CH:20]([C:26]([OH:28])=[O:27])[CH2:21]SC(=O)C)(=O)[CH3:17]>>[C:6]([O:28][C:26](=[O:27])[C@@H:20]1[CH2:21][CH2:17][CH2:16][N:19]1[C:13](=[O:15])[C@H:5]([C:6]([S:9][C:10](=[O:12])[CH3:11])([CH3:7])[CH3:8])[NH:4][C:1](=[O:3])[CH3:2])([CH3:8])([CH3:7])[CH3:5]

Participants

3

Reactant 2

HCID 4321391HCID 4321391, compoundHCID 18609577N,S-diacetyl-penicillamine

Product 1

HCID 54234986N-acetyl-3-acetylthiovalyl-L-proline t-butyl ester

Procedure

By substituting N,S-diacetyl-penicillamine for the N,S-diacetyl-D,L-cysteine in the procedure of Example 53, N-acetyl-3-acetylthiovalyl-L-proline t-butyl ester is obtained.

Sources & evidence

ORD record
ord-2502f5778fdc4323bec889e830d829d2
Source dataset
uspto-grants-1988_03
Patent number
US04734420

Reaction notes

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