Dicyclohexylcarbodiimide → HCID 54504018, compound

Participants

Reaction Steps

To a solution of L-proline t-butyl ester (1.71 g.) and 3-hydroxybenzotriazole (1.35 g.) in dichloromethane (15 ml.) dicyclohexylcarbodiimide (2.06 g.) and the product from Example 79 (2.2 g.) are added. After 18 hours stirring at room temperature, the precipitate formed is filtered off, the filtrate is washed neutral, dried and concentrated to dryness to yield 3.7 g. of the named product Rf : 0.8 (silica gel-ethyl acetate).

Provenance & Evidence