Cyclohexylamine → HCID 13769879, compound

Participants

Reaction Steps

Dissolved in 40 ml of isoamyl alcohol was 2.0 g (5.34 mmol) of ethyl 2(4-benzylpiperazino)-4-chloromethylpyrimidine-5-carboxylate, followed by an addition of 10.5 g (107 mmol) of cyclohexylamine. The resultant mixture was refluxed for 6 hours. After completion of the reaction, the solvent was distilled off and the residue was washed with ether to obtain 1.32 g of the above-identified compound as crystals (yield: 63%).

Provenance & Evidence