反应详情

1.80 g (3.40 mmol) of ethyl 4-({2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methoxybutanoyl}amino)benzoate (racemate) in 45 ml of methanol/water (4/1) were reacted with 2.24 g (6.87 mmol) of caesium carbonate according to General Method 4, giving the title compound. Yield: 1.66 g (88% of theory)