Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 57025Generated: October 30, 2026

Trifluoroacetic acid → HCID 117623009, compound

https://huagongshe.com/reaction/57025

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-Butyl 4-({[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl](ethoxy)acetyl}amino)benzoateHCID 117622697—
ProductHCID 117623009HCID 117623009—

Reaction Steps

260 mg (0.48 mmol) of tert-butyl 4-({[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl](ethoxy)acetyl}amino)benzoate (racemate) were hydrolysed with TFA according to General Method 2. Yield: 184 mg (79% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434690B2
Source datasetuspto-grants-2016_09
ORD IDord-ae21029c4b7c4ffeaefb511932fa3ec4
Source noteuspto-grants-2016_09