反应详情

This compound was prepared in an analogous manner as 3-{[3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester using 3-(aminomethyl)pyridine instead of 1-BOC-3-aminopyrrolidine. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.54 (1H, br. s.) 10.28 (1H, s) 8.73 (1H, t, J=6.05 Hz) 8.55 (1H, d, J=1.76 Hz) 8.45 (1H, dd, J=4.78, 1.66 Hz) 8.02 (1H, d, J=5.47 Hz) 7.81 (1H, d, J=5.47 Hz) 7.67-7.74 (1H, m) 7.50 (1H, d, J=5.47 Hz) 7.28-7.38 (2H, m) 6.84 (1H, d, J=5.47 Hz) 6.42 (1H, dd, J=3.42, 1.85 Hz) 4.48 (2H, d, J=6.05 Hz)