Benzenemethanamine, 3-chloro- → HCID 50924294, compound

Participants

Reaction Steps

This compound was prepared in an analogous manner as 3-{[3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester using 3-chlorobenzylamine instead of 1-BOC-3-aminopyrrolidine. LCMS (ESI) 383 (M+H) 1H NMR (400 MHz, DMSO-d6) δ ppm 11.53 (1H, br. s.) 10.27 (1H, s) 8.72 (1H, t, J=5.95 Hz) 8.03 (1H, d, J=5.47 Hz) 7.82 (1H, d, J=5.47 Hz) 7.50 (1H, d, J=5.47 Hz) 7.21-7.41 (5H, m) 6.84 (1H, d, J=5.47 Hz) 6.41 (1H, dd, J=3.51, 1.95 Hz) 4.46 (2H, d, J=5.86 Hz)

Provenance & Evidence