4-Chloroaniline → HCID 50924296, compound

Participants

Reaction Steps

This compound was prepared in an analogous manner as 3-{[3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester using 4-chloroaniline instead of 1-BOC-3-aminopyrrolidine. LCMS (ESI) 369 (M+H) 1H NMR (400 MHz, DMSO-d6) δ ppm 11.56 (1H, br. s.) 10.12 (1H, s) 9.99 (1H, s) 8.04 (1H, d, J=5.47 Hz) 7.91 (1H, d, J=0.10 Hz) 7.71 (2H, d, J=8.93 Hz) 7.52 (1H, d, J=5.37 Hz) 7.37-7.43 (2H, m) 7.33 (1H, dd, J=3.25, 2.61 Hz) 6.85 (1H, d, J=5.42 Hz) 6.46 (1H, dd, J=3.49, 1.88 Hz)

Provenance & Evidence