Indole-5-carboxaldehyde → HCID 50924617, compound

Participants

Reaction Steps

This compound was prepared in an analogous manner as 3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid [2-(4-methoxy-benzylamino)-ethyl]amide using indole-5-carboxaldehyde instead of 4-methoxy benzaldehyde. LCMS (ESI) 431 (M+H) 1H NMR (400 MHz, DMSO-d6) δ ppm 11.49 (1H, br. s.) 10.93 (1H, br. s.) 10.27 (1H, s) 7.96-8.06 (1H, m) 7.75 (1H, d, J=5.47 Hz) 7.41-7.51 (1H, m) 7.22-7.31 (1H, m) 7.02 (1H, dd, J=8.30, 1.46 Hz) 6.78 (1H, d, J=5.47 Hz) 6.41 (1H, dd, J=3.51, 1.76 Hz) 6.30 (1H, dd, J=2.54, 1.56 Hz) 3.73 (2H, s) 3.33 (2H, d, J=5.86 Hz) 2.64 (2H, t, J=6.25 Hz)

Provenance & Evidence