3-Chloro-4-fluorobenzaldehyde → HCID 50924761, compound

Participants

Reaction Steps

This compound was prepared in an analogous manner as 3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid [2-(4-methoxy-benzylamino)-ethyl]amide using 3-chloro-4-fluorobenzaldehyde instead of 4-methoxy benzaldehyde. LCMS (ESI) 444 (M+H) 1H NMR (400 MHz, DMSO-d6) δ ppm 11.52 (1H, br. s.) 10.27 (1H, s) 7.99-8.07 (2H, m) 7.77 (1H, d, J=5.47 Hz) 7.52 (1H, d, J=7.91 Hz) 7.46 (1H, d, J=5.42 Hz) 7.29 (3H, dd, J=1.24, 0.17 Hz) 6.80 (1H, d, J=5.47 Hz) 6.42 (1H, dd, J=3.47, 1.85 Hz) 3.66 (2H, s) 2.61 (2H, t, J=6.59 Hz)

Provenance & Evidence