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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 57052Generated: October 30, 2026

Lithium Hydroxide → HCID 117622907, compound

https://huagongshe.com/reaction/57052

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantEthyl 6-({2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-methylbutanoyl}amino)-1H-benzimidazole-2-carboxylateHCID 117622331—
ProductHCID 117622907HCID 117622907—

Reaction Steps

130 mg (237 μmol) of ethyl 6-({2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-methylbutanoyl}amino)-1H-benzimidazole-2-carboxylate (racemate) were hydrolysed with lithium hydroxide according to General Method 3. Yield: 56 mg (44% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434690B2
Source datasetuspto-grants-2016_09
ORD IDord-6d3829465417478c947a4e71fedae2b3
Source noteuspto-grants-2016_09