2-(4-(3-(4-Chlorophenyl)-1,2,4-thiadiazol-5-yl)piperazin-1-yl)-1-(4-methoxyphenyl)ethanol → 2-{4-[3-(4-Chloro-phenyl)-[1,2,4]thiadiazol-5-yl]-piperazin-1-yl}-1-(3-methoxy-phenyl)-ethanol

Participants

Reaction Steps

In analogy to the procedure described for the synthesis of 2-{4-[3-(4-Chloro-phenyl)-[1,2,4]thiadiazol-5-yl]-piperazin-1-yl}-1-(4-methoxy-phenyl)-ethanol (Example 54) the title compounds was prepared from 2-{4-[3-(4-Chloro-phenyl)-[1,2,4]thiadiazol-5-yl]-piperazin-1-yl}-1-(3-methoxy-phenyl)-ethanone through reduction as white solid. MS (m/e): 431.3 (MH+).

Provenance & Evidence