Hydrazine → HCID 56847267, compound

Participants

Reaction Steps

To a suspension of 2-[2-[4-[2-(3,5-dimethoxyanilino)-[1,2,4]triazolo[1,5-a]pyrazin-8-yl]piperazin-1-yl]ethyl]isoindoline-1,3-dione in ethanol is added hydrazine (20 eq) and the clear colorless solution is refluxed for 2 h and monitored by HPLC. The solvent is removed under reduced pressure and the residue purified via preparative HPLC yielding the title compound “D20”;

Provenance & Evidence